ProbioBrain™

The gut-brain axis is a biological network comprising the gut (gastrointestinal tract), the enteric nervous system (our ‘second brain’ which regulates gastrointestinal function), and the brain. Bidirectional communication along this network is critical for regulation of important functions in the body such as immunity, digestion, metabolism, satiety, and the stress response.¹⁷ The vagus nerve is a long, wandering nerve extending from the brainstem in the back of the brain into organs located in the neck, chest, and abdomen, including the intestines. The vagus nerve not only carries signals from the brain but also carries sensory signals from the gut back to the brain. This allows the brain to sense the environment within the gut! Microbes within the gut can produce neurotransmitters and neuroactive molecules that can influence the brain. The scientific evidence shows that our gut microbes can influence how our brain functions, how we respond to stress, our mood, and even how we behave.^18,19 The microbiota-gut-brain axis therefore plays an essential role in our overall health, including mental wellness and cognitive health.  

What’s exciting is that this very signaling system is paving the way for pioneering supplements that can improve everyday health concerns with a mental component. One area of interest is the growing body of research on psychobiotics. Psychobiotics is a term to describe any exogenous influence (i.e., probiotics, prebiotics, dietary fiber) whose positive effect on mental health is bacterially mediated.¹⁶